What does methyl salicylate react with?
Methyl salicylate (oil of wintergreen) is an organic ester. When an acid (containing the –COOH group) reacts with an alcohol (a compound containing an –OH group) formed an ester.
What is the mode of action of methyl salicylate?
Methyl salicylate relieve musculoskeletal pain in the muscles, joints, and tendons by causing irritation and reddening of the skin due to dilated capillaries and increased blood flow. It is pharmacologically similar to aspirin and other NSAIDs but as a topical agent it primarily acts as a rubefacient and skin irritant.
What type of chemical reaction is involved in methyl salicylate formation?
When salicylic acid is heated with methyl alcohol, the carboxyl group of salicylic acid is esterified producing a strong-smelling liquid ester (methyl salicylate). an alcohol and a carboxylic acid. The reaction is reversible and uses an acid as a catalyst.
What functional groups are in methyl salicylate?
The given compound methyl salicylate is shown as: In the compound, the functional groups are alcohol (OH) and ester group (COO).
What kind of reaction is the conversion of methyl salicylate to salicylic acid?
saponification reaction
Methyl salicylate can be converted into salicylic acid using the saponification reaction. You will perform this reaction and will purify the product using crystallization.
What are the roles of methyl salicylate in the synthesis of salicylic acid?
Methyl salicylate (an ester) can be hydrolyzed to produce salicylic acid. The two different functional groups on the aromatic ring are utilized in this lab. First, the free carboxylic acid group will be produced when we hydrolyze the methyl salicylate. Methanol is the alcohol which is released by hydrolysis.
What is methyl salicylate functional group?
In methyl salicylate (on the left) the benzene ring is substituted by two functional groups, a hydroxyl group (-OH) and an ester group (-COOCH3).
How does methyl salicylate turn into salicylic acid?
Why is methyl salicylate important?
For acute joint and muscular pain, methyl salicylate is used as a rubefacient and analgesic in deep heating liniments. It is used as a flavoring agent in chewing gums and mints in small concentrations and added as antiseptic in mouthwash solutions.
What is methyl salicylate?
Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. The compound was first extracted and isolated from plant species Gaultheria procumbens in 1843. It can be manufactured synthetically and it used as a fragrance, in foods, beverages, and liniments.
What is the half life of methyl salicylate at pH 8?
The base-catalyzed rate constant can be estimated to be 4.0X10-2 L/mole-sec if the ortho consituents to the phenyl ring are ignored (4). The half-life of methyl salicylate calculated from this rate constant is 201 days at pH 8 (SRC).
What is the KOC value of methyl salicylate?
The Koc for methyl salicylate estimated from molecular structure is 128 (1) and is 33 (3,SRC) estimated from its water solubility, 7400 mg/L (2), using a regression equation. According to a suggested classification scheme (4), these low Koc values suggest that methyl salicylate would be highly or very highly mobile in soil (SRC).
What are the signs and symptoms of methyl salicylate toxicity?
Symptoms of poisoning by methyl salicylate differ little from those described for aspirin. Central excitation, intense hyperpnea, and hyperpyrexia are prominent features. The odor of the drug can easily be detected on the breath and in the urine and vomitus.