What do hexokinase and glucokinase have in common?

Glucokinase and Hexokinase are enzymes which phosphorylate glucose to glucose-6-phosphate, trapping glucose inside the cell.

What reactions do hexokinase and glucokinase catalyze?

Both hexokinase and glucokinase catalyze the same reaction of glycolysis. Hexokinase is present in almost all tissues while glucokinase is present in the liver and beta cells of the pancreas. They use ATP to convert glucose into glucose 6-phosphate.

What is the Km value of hexokinase and glucokinase?

Glucokinase: Km = 10 mM, not inhibited by glucose 6-phosphate. Present in liver and in pancreas b cells. Hexokinase: Km= 0.2 mM, inhibited by glucose 6-phosphate. Present in most cells.

What is the difference between hexokinase and glucokinase?

Furthermore, hexokinase has a high affinity towards glucose while glucokinase has a low affinity towards glucose. Hexokinase and glucokinase are two enzymes involved in the conversion of glucose into glucose 6-phosphate (G6P) during glycolysis. 1. What is Hexokinase 2. What is Glucokinase 3.

Why does Hexokinase I-III have a high affinity for glucose?

Also, the Km value and the Vmax of hexokinase I-III is low, giving a high affinity towards glucose and low capacity, respectively. The low capacity of the enzyme helps to saturate the enzyme even in the presence of low levels of glucose. Hexokinase I-III are allosteric enzymes, which are inhibited by the high amounts of G6P.

What are the 4 types of hexokinase?

The four main types of hexokinases are hexokinase I, II, III, and IV. The first three hexokinases, hexokinase I-III, can be found in all cells of the body while hexokinase IV or glucokinase is only found in the liver cells and β-pancreatic cells.

What is the function of glucokinase?

Glucokinase is a type of hexokinase only found inside the liver cells and β-pancreatic cells. They have a vital role in carbohydrate metabolism.