What are the classifications of pharmaceutical drugs?
DREs classify drugs in one of seven categories: central nervous system (CNS) depressants, CNS stimulants, hallucinogens, dissociative anesthetics, narcotic analgesics, inhalants, and cannabis.
How are drugs classified as per BCS?
The drugs are classified in BCS on the basis of solubility, permeability, and dissolution. Solubility class boundaries are based on the highest dose strength of an immediate release product.
What are BCS Class 2 drugs?
BCS Class IIa drugs, typically carboxylic acids with a pKa in the range of 4 to 5, are insoluble at typical, fasted, gastric pHs but soluble at intestinal pHs and, hence, are classified as BCS Class II or IV depending on intestinal jejunal permeability at pH = 6.5 or fraction dose absorbed determination in humans.
What are the 3 categories of medicines?
The Act defines three categories of medicine: prescription only medicines (POM), which are available only from a pharmacist if prescribed by an appropriate practitioner (including, but not limited to doctors, dentists, optometrists and nurses); pharmacy medicines (P), available only from a pharmacist but without a …
What are the 10 classification of drugs?
Drug Classifications
- Cannabis.
- Depressants.
- Dissociative anesthetics.
- Hallucinogens.
- Inhalants.
- Opioids.
- Stimulants.
What are BCS Class 1 drugs?
By definition, BCS Class I drugs are highly absorbed, and have neither solubility nor permeability limited absorption. Therefore they generally represent a low risk group of compounds in terms of the potential for excipients to affect absorption, compared to other BCS classes.
What is BCS IV?
Purpose: Biopharmaceutics classification system (BCS) class IV compounds, exhibits least oral bioavailability, low solubility and intestinal permeability among all pharmaceutical classes of drugs. Thus, these drugs need more compatible and efficient delivery system.
What are BCS Class 3 drugs?
BCS Class III drug substances are considered to be more susceptible to the effects of excipients. These drugs are not considered highly permeable and may have site-specific absorption, so there are a greater number of mechanisms through which excipients can affect their absorption than for BCS Class I drugs.