What causes baby splenomegaly?
Excessive antigenic stimulation due to infection is the cause of most cases of splenomegaly in children. Viral infections are the most frequent culprits, and the associated splenomegaly is usually transient and only mild to moderate in severity.
What are 2 most common causes of splenomegaly?
Causes
- Viral infections, such as mononucleosis.
- Bacterial infections, such as syphilis or an infection of your heart’s inner lining (endocarditis)
- Parasitic infections, such as malaria.
- Cirrhosis and other diseases affecting the liver.
Does pregnancy cause splenomegaly?
The cause of splenomegaly in pregnancy is not known. A possible explanation might be related to the cardiovascular and haemodynamic changes that occur during pregnancy [13]. Blood volume increases gradually over the gestation period, reaching a 40% increase by term [13].
Is splenomegaly common in children?
On physical examination, splenomegaly is generally defined as a palpable splenic edge felt >2 cm below the left costal margin. A palpable spleen tip may be a normal finding in up to 30 percent of neonates; the frequency drops to approximately 10 percent in healthy school-age children and <3. percent in young adults.
What are the causes of splenomegaly in children?
Splenomegaly in children. Identifying the cause Splenomegaly is usually the result of systemic disease. The differential diagnosis can logically be subdivided into infectious, hematologic, metabolic, vascular, and neoplastic diseases which result in abnormalities of the lymphoid, reticuloendothelial, or vascular components of the spleen. Splenic …
What is splenomegaly and how is it treated?
Splenomegaly is a symptom that can be caused by a variety of conditions that affect different organ systems. When evaluating a child with splenomegaly it is important to identify conditions in which immediate medical intervention is needed and provide appropriate treatment options.
What is mild splenomegaly on ultrasound?
Mild splenomegaly is a finding in younger adults (83). In one half of the children with FMF splenomegaly is detectable by ultrasound (84). The increase in size of the spleen seems to be higher during attacks compared to attack-free periods (85).
What is the most common grade of splenomegaly in the US?
Most common grade of splenomegaly was grade III (33%) of Hackett’s classification. The most common presenting symptom was fever (75%) and sign was pallor (97%). Most common cause of splenomegaly was hemolytic anemia (80.64%) among which thalasemia was 50% followed by sickle cell anemia 30.64%.